Cold Spring Harbor Laboratory is hosting the course, Statistical Analysis of Genome Scale Data, June 5-19, 2025. Harmen Bussemaker, from Columbia University, Sean Davis, from the University of Colorado Anschutz School of Medicine, and Hans Tomas Rube, from the University
A genome-wide association study of sorghum seedlings under salt stress identified 35 loci and 39 candidate genes—many conserved across species—implicated in salt sensing, ROS detoxification, osmotic adjustment, and K⁺/Na⁺ homeostasis, providing targets for improving salt tolerance through molecular breeding.
Synthetic apomixis was successfully engineered in hybrid sorghum, enabling clonal seed formation that preserves hybrid heterozygosity across generations, although further optimization is needed to improve fertility and developmental stability.
The sorghum genotype ‘S208’ exhibits superior waterlogging tolerance through coordinated activation of anaerobic energy metabolism, hormone signaling, and cell wall remodeling that drives adventitious root formation and aerenchyma development under hypoxic conditions.
Understanding sorghum grain quality is essential for breeding, food innovation, and industrial applications. Traits such as protein, starch composition, oil content, tannins, and phenolic compounds directly influence nutritional value, processing behavior, and end use. However, traditional laboratory assays are slow,
Sorghum (Sorghum bicolor) has long played a central role in the production of fermented beverages across continents, from West African dolo and pito to Chinese baijiu and emerging gluten-free craft beers in the West. A wave of recent research is shedding light on how sorghum’s grain properties, microbial interactions during fermentation, and genetic diversity influence the quality and sustainability of these beverages.
In recent years, sorghum has gained increasing attention not just as a climate-resilient staple crop, but also as a source of high-value bioactive compounds with applications beyond the food and feed sectors. A growing body of research highlights the potential of sorghum storage proteins—particularly kafirins—as a sustainable source of antioxidant peptides and cosmeceutical ingredients.
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