SorghumBase blog

Advancing Sorghum Genomics: Design and Application of the Twist 100K Genotyping Array

SorghumBase invites the global sorghum research and breeding community to join an upcoming webinar taking place March 31st on the design and implementation of the Twist 100K genotyping array, a next-generation resource developed through broad community engagement and cutting-edge genomic approaches.

Single Cell & Spatial Transcriptomics Analysis course Will Be Held Jun 25- Jul 13, 2026 at CSHL, Applications Due Mar 27

Cold Spring Harbor Laboratory is hosting the Single Cell & Spatial Transcriptomics Analysis course, June 25-July 13. This intensive two-week course trains students in state-of-the-art wet-lab methods for single-cell analysis and builds foundational skills in bioinformatic handling of single-cell data.

CSHL Statistical Analysis of Genome Scale Data Course, June 5-19, Applications due March 13

Cold Spring Harbor Laboratory is hosting the course, Statistical Analysis of Genome Scale Data, June 5-19, 2025. Harmen Bussemaker, from Columbia University, Sean Davis, from the University of Colorado Anschutz School of Medicine, and Hans Tomas Rube, from the University

Heme-Dependent Dimerization and ER Membrane Remodeling by the Sorghum Membrane Steroid Binding Protein SbMSBP1

SbMSBP1 is an ER-localized MAPR protein in sorghum that binds heme, undergoes heme-dependent dimerization, and promotes membrane remodeling, suggesting roles in vesicle trafficking, cytochrome P450 stabilization, and stress-adaptive specialized metabolism.

Genetic Architecture and Co-Localized QTL Underlying Plant Height and Brix Content in Sorghum

Genetic modeling and high-density QTL mapping reveal that sorghum plant height and brix content are governed by interacting major genes and polygenes, share co-localized loci that explain their phenotypic correlation, and are influenced by auxin- and carbon-fixation–related candidate genes that offer targets for breeding improved varieties.

Engineering Leaf Angle in Sorghum to Enhance Canopy Efficiency and Water Use

Targeted knockdown of SbLG1 and SbLG2 in sorghum reduces leaf angle to enhance light distribution, photosynthetic efficiency, and biomass yield without increasing water use, advancing the development of a ‘smart canopy’ architecture.

High-Throughput, Nondestructive Grain Quality Analysis in Sorghum

Understanding sorghum grain quality is essential for breeding, food innovation, and industrial applications. Traits such as protein, starch composition, oil content, tannins, and phenolic compounds directly influence nutritional value, processing behavior, and end use. However, traditional laboratory assays are slow,

Sorghum in Fermentation: New Insights into Genetics, Grain Traits, and Microbial Interactions from Baijiu to African Traditional Beers

Sorghum (Sorghum bicolor) has long played a central role in the production of fermented beverages across continents, from West African dolo and pito to Chinese baijiu and emerging gluten-free craft beers in the West. A wave of recent research is shedding light on how sorghum’s grain properties, microbial interactions during fermentation, and genetic diversity influence the quality and sustainability of these beverages.

Unlocking Sorghum’s Potential in Skin Care and Antioxidant Applications: A New Frontier for Kafirin Peptides

In recent years, sorghum has gained increasing attention not just as a climate-resilient staple crop, but also as a source of high-value bioactive compounds with applications beyond the food and feed sectors. A growing body of research highlights the potential of sorghum storage proteins—particularly kafirins—as a sustainable source of antioxidant peptides and cosmeceutical ingredients.

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